Managing Side Effects

ELIGARD Side Effects

ELIGARD – A Hormonal Therapy for Prostate Cancer

ELIGARD is a prescription medication for the palliative treatment (management of symptoms) of advanced prostate cancer. ELIGARD is an LHRH (luteinizing hormone-releasing hormone) agonist. It is designed to reduce the amount of testosterone in the body by reducing the testicles' production of testosterone. It is not a cure for advanced prostate cancer.

ELIGARD is now available in 4 different prescription doses, giving you and your physician flexible dosing options for treating your advanced prostate cancer. The ELIGARD 45 mg shot, the newest addition to the ELIGARD family, is the first and only 6-month hormone therapy for the treatment of advanced prostate cancer. ELIGARD 45 mg gives you the benefit of a full year of hormone therapy with just 2 injections. Ask you doctor about twice-yearly ELIGARD.

Like all LHRH agonists, ELIGARD decreases the level of male hormones in the body. As a result, ELIGARD may cause some side effects. The good news is that there are things you can do to help manage ELIGARD side effects.

It's important that you pay attention to how you're feeling and share that information with your doctor or nurse. They may have suggestions beyond what's on this web site on how to manage the effects.

For more information, see the ELIGARD Prescribing Information or talk to your doctor or nurse.

Dose	Side Effects
Most Common Side Effects of ELIGARD (reported by 2% or more of men)
ELIGARD 7.5 mg	Fatigue Dizziness Hot flashes/sweats Decrease in the size of the testes Inflammation of the stomach/intestine
ELIGARD 22.5 mg	Hot flashes/sweats Fatigue Urinary frequency Nausea Itching Joint Pain
ELIGARD 30 mg	Hot flashes Fatigue Testicular atrophy (decrease in the size of the testes) Gynecomastia (breast growth) Testicular pain Clamminess Night sweats Hair loss Frequent need to urinate, especially at night Dizziness Decreased libido Myalgia (muscle pain) Nausea
ELIGARD 45 mg	Hot flashes Fatigue Weakness Testicular atrophy (decrease in the size of the testes) Gynecomastia (breast growth) Night sweats Myalgia (muscle pain) Pain in limb

Dosing	Side Effects
Less Common Side Effects of ELIGARD (reported by fewer than 2% of men)
ELIGARD 7.5 mg	Sweating Syncopy (fainting) Insomnia (sleeplessness) Light-headedness Intestinal gas Constipation Decreased red blood cell count, hematocrit, and hemoglobin Weight gain Tremor Backache Joint pain Disturbance of smell and taste Depression Vertigo Hair loss Testicular soreness Inability to have or maintain an erection Decreased libido Gynecomastia (breast growth) Breast soreness
ELIGARD 22.5 mg	Dyspepsia (indigestion) Rigors (chill) Weakness Lethargy (mild impairment of consciousness) Difficulties with urination Pain on urination Scanty urination Bladder spasm Blood in urine Urinary retention Breast tenderness Decrease in the size of the testes Testicular pain Gynecomastia (breast growth) Inability to have or maintain an erection Clamminess Night sweats, increased sweating Hypertension (high blood pressure) Hypotension (low blood pressure)
ELIGARD 30 mg	Lethargy (mild impairment of consciousness) Gynecomastia (breast growth) Inability to have or maintain an erection Reduced penis size Urinary urgency Incontinence Insomnia (sleeplessness) Depression Muscle atrophy Limb pain
ELIGARD 45 mg	Lethargy (mild impairment of consciousness) Reduced penis size Nocturia (excessive nighttime urination) Nocturia aggravated Loss of libido

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Remember, Eligard is available by Rx only and your doctor is the single best source of information regarding you and your health.
Please consult your doctor if you have any questions about your health or your medication.

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Indications and Important Safety Information

Indication
ELIGARD is a prescription drug, given by injection, for the management of advanced prostate cancer. However, there is no known cure for prostate cancer.

Important Information
ELIGARD should not be used by women, children, or anyone who is allergic to the drug leuprolide acetate or any of the ingredients of ELIGARD.

ELIGARD, like other drugs in its class, causes a temporary increase in testosterone during the first weeks of treatment. Patients may experience worsening of symptoms or new symptoms during the first weeks of treatment, including bone pain, nerve damage, blood in the urine, or difficulty urinating. The most common side effects are hot flashes, injection site pain (including burning and stinging), fatigue, and testicular atrophy.

Please see patient information for important additional information.