For U.S. Residents Only

LHRH (luteinizing hormone-releasing hormone) agonists work to manage the symptoms of prostate cancer by blocking the production of male hormones. Therefore, they can cause certain side effects related to a decrease in male hormone levels. ELIGARD® (leuprolide acetate for injectable suspension) is a type of LHRH agonist, but the side effects covered in this section are general side effects associated with the entire group of LHRH agonists. For information on side effects specific to ELIGARD, see the section titled "Side Effects of ELIGARD."

Talk to Your Doctor

If you're having side effects from your LHRH agonist prostate cancer treatment, talk to your doctor or nurse to determine the causes and possible ways to manage them.

Common Side Effects of LHRH Agonist Therapy
  • Breast growth (gynecomastia) and/or sensitivity (mastodynia)
  • Weight gain
  • Loss of muscle mass and strength
  • Loss of testicular and penile volume
  • Loss of body hair
  • Change in head hair, beard
  • Loss of bone mineral density
  • Low red blood count (anemia)
  • Lipid changes
  • Sexual dysfunction
  • Inability to achieve or maintain an erection
  • Hot flashes
  • Lack of energy or initiative
  • Mood swings

Questions to Ask Your Doctor
  • What side effects am I likely to experience?
  • Can you recommend ways to manage side effects?
  • Are the side effects permanent or temporary?
  • Are there certain foods that might help?
  • What form of exercise is right for me?
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