For U.S. Residents Only
LHRH AGONISTS SIDE EFFECTS
LHRH (luteinizing hormone-releasing hormone) agonists work to manage the symptoms
of prostate cancer by blocking the production of male hormones. Therefore, they
can cause certain side effects related to a decrease in male hormone levels. ELIGARD®
(leuprolide acetate for injectable suspension) is a type of LHRH agonist, but the
side effects covered in this section are general side effects associated with the
entire group of LHRH agonists. For information on side effects specific to ELIGARD,
see the section titled "Side
Effects of ELIGARD."
Talk to Your Doctor
If you're having side effects from your LHRH agonist prostate cancer treatment,
talk to your doctor or nurse to determine the causes and possible ways to manage
them.
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Common Side Effects of LHRH Agonist Therapy |
- Breast growth (gynecomastia)
and/or sensitivity (mastodynia)
- Weight gain
- Loss of muscle mass and strength
- Loss of testicular and penile volume
- Loss of body hair
- Change in head hair, beard
- Loss of bone mineral density
- Low red blood count (anemia)
- Lipid changes
- Sexual dysfunction
- Inability to achieve or maintain an erection
- Hot flashes
- Lack of energy or initiative
- Mood swings
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- What side effects am I likely to experience?
- Can you recommend ways to manage side effects?
- Are the side effects permanent or temporary?
- Are there certain foods that might help?
- What form of exercise is right for me?
Have you ever been treated with a hormonal therapy?
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LHRH agonist 0% |
|
antiandrogen therapy 0% |
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estrogen therapy 0% |
|
orchiectomy (surgery) 0% |
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combination therapy 0% |
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no 0% |
Indication
ELIGARD is a prescription drug, given by injection, for the management of advanced
prostate cancer. However, there is no known cure for prostate cancer.
Important Safety Information
ELIGARD should not be used by women, children, or anyone who is allergic to the
drug leuprolide acetate or any of the ingredients of ELIGARD.
ELIGARD, like other drugs in its class, causes a temporary increase in testosterone
during the first week of treatment. Patients may experience worsening of symptoms
or new symptoms during the first weeks of treatment, including bone pain, nerve
damage, blood in the urine, or difficulty urinating. The most common side effects
are hot flashes, injection site pain (including burning and stinging), fatigue,
and testicular atrophy.
Please see and full mixing and administration instructions.
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